The Glasgow rivals have both endured mixed starts to the new campaign, with the Gers crashing out of the Champions League in midweek.
Michael Beale’s side also suffered a surprise 1-0 defeat to Kilmarnock on the opening weekend of the new Premiership season.
But Rangers can leapfrog Celtic at the top of the table with their second successive victory in this fixture following a 3-0 triumph in May.
That win proved to be the first in nine for the Blues but came when the Hoops had already confirmed their 11th title in 12 years.
Brendan Rodgers will be expecting an improved showing from his side with more to play for this time.
However, Celtic are not in the best form either having drawn at home to St Johnstone days after their League Cup elimination